Pernice was last seen by her husband at the family home in the Northland area of Kansas City, MO. She works as a nurse and a nursing instructor at St. Luke's Hospital. Family report Renee's purse and car keys were left at the house, but officers with the Kansas City Police said a passerby found her cell phone discarded on a city street. It is very unusual for Renee to leave her children or her job. Her husband, Shon Pernice pled guilty to murdering Renee. The location of her remains is unknown.