Thresher had dinner with her family during the evening of May 23, 2000 in Bethesda, Maryland. She returned to her residence in Sumner Highlands Apartments in the 4500 block of Sangamore Road later that night. Thresher spoke to an acquaintance on the telephone at approximately 10:00 PM and e-mailed her employer at 12:00 AM on May 24. Thresher has not been heard from since.